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Yoel Sadovsky, MD

Dr. Yoel Sadovsky


Fax: 412-641-3898
A608 Magee Womens Research Institute


MD, Hebrew University - Hadassah Medical School, Jerusalem (Israel)

B Med Sci, Hebrew University - Hadassah Medical School, Jerusalem (Israel)

Academic Affiliation(s)

Professor, Department of Obstetrics, Gynecology and Reproductive Sciences

Professor, Department of Microbiology and Molecular Genetics

Professor, Clinical and Translational Science Institute

Director, Magee Womens Research Institute

Member, Molecular Genetics and Developmental Biology Graduate Program

Member, Molecular Virology and Microbiology Graduate Program


Research in the Sadovsky lab centers on feto-placental development. Using human placental cells (trophoblasts) as well as mouse models, the lab studies molecular pathways that govern placental adaptive response to injury. Primary areas of inquiry include:  (1) the role of microRNAs in placental function, combining computationally identified sets of miRNA targets, RNAseq, and functional assays to decipher the critical role of unique placental microRNAs in viral replication and cellular resistance to viruses, (2) microRNA packaging and trafficking within exosomes, and (3) placental uptake, storage and mobilization of metabolic fuels, centering on fatty acids that are critical for feto-placental development.

Lab Personnel

Faculty: Jacob Larkin, MD; Takuya Mishima, MD, PhD; Jean-Francois Mouillet, PhD; Xiao-Hua Shi, MD

Postdoctoral fellows: Mayumi Morizane, MD; Yingshi Ouyang, PhD

Lab staff: Lori Rideout, BA (Lab Admin); Elena Sadovsky, RN; HuiJie Sun, BSc; Judy Ziegler, BSc

Graduate student: Avraham Bayer, BSc

Areas of Interest

Placental development; placental fat metabolism; the function and trafficking of placental miRNAs