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Seema Lakdawala, PhD

Dr. Seema Lakdawala


Fax: 412-624-2139
421 Bridgeside Point 2
450 Technology Drive


PhD in Biological Sciences, University of California

BSc in Natural Sciences, University of Texas

Academic Affiliation(s)

Assistant Professor, Department of Microbiology and Molecular Genetics

Member, Molecular Virology and Microbiology


Influenza A viruses pose a major public health risk from seasonal epidemics and sporadic pandemics. My lab studies the molecular properties contributing to the epidemiological success of influenza A viruses to better predict future pandemics. There are two main areas of research in my lab 1) exploring the intracellular dynamics of influenza viral RNA assembly and 2) defining the viral properties necessary for efficient airborne transmission of influenza viruses.

Lab Personnel

Amar Bhagwat (Research Assistant Professor)

Eric Nturibi (Technician)

Valerie Le Sage (Research Associate)

Karen Kormuth (Postdoctoral Fellow)

Areas of Interest

Virology, Emerging influenza viruses, Virus Assembly, Virus Transmission, Microscopy, Live Cell Imaging


Lakdawala S.S, Jayaraman A, Halpin R.A, Lamirande E.W, Shih A.R, Stockwell T.B, Lin X, Simenauer A, Hanson C.T, Vogel L, Paskel M, Minai M, Moore I, Orandle M, Das S.R, Wentworth D.E, Sasisekharan R. and Subbarao K. The soft palate is an important site of adaptation for transmissible influenza viruses. Nature. 526: 122-125. |  View Abstract

Lakdawala S.S, Wu Y, Wawrzusin P, Kabat J, Broadbent A.J, Lamirande E.W, Fodor E, Altan-Bonnet N, Shroff H. and Subbarao K. Influenza a virus assembly intermediates fuse in the cytoplasm. PLoS Pathog. 10: e1003971. |  View Abstract

Lakdawala S.S, Shih A.R, Jayaraman A, Lamirande E.W, Moore I, Paskel M, Sasisekharan R. and Subbaro K. Receptor specificity does not affect replication or virulence of the 2009 pandemic H1N1 influenza virus in mice and ferrets. Virology. 446: 349-356. |  View Abstract

Lakdawala, S.S. and Subbarao K. The ongoing battle against influenza: The challenge of flu transmission. Nat Med. 18: 1468-1470. |  View Abstract

Lakdawala S.S, Lamirande E.W, Suguitan A.L., Jr., Wang W, Santos C.P, Vogel L, Matsuoka Y, Lindsley W.G, Jin H and Subbarao K. Eurasian-origin gene segments contribute to the transmissibility, aerosol release, and morphology of the 2009 pandemic H1N1 influenza virus. PLoS Pathog. 7: e1002443. |  View Abstract

Luke C, Lakdawala S.S. and Subbarao K. "Chapter 16: Influenza Vaccine-Live." VACCINES, Sixth Ed., Elsevier.