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Matthew J. Brown, PhD








				

		Dr. Matthew J. Brown	
		

		    	
        
Contact
        
	
		
			
        
		
		
        
                
        



	

	
Mentor
Dr. Gerard J. Nau
	
	


	

	
Dissertation
The Contribution of One-carbon Metabolism to the Pathogenesis of Francisella tularensis
	
	




	

	
Education
PhD in Molecular Virology and Microbiology, University of Pittsburgh, School of Medicine, 2013
BS in Biological Sciences with specialty in Molecular Genetics, University of Rochester, 2008
	



    

























	

	
Why I chose Pitt
Following his graduation, Matt accepted a post-doctoral research   position at the University of Michigan where he will be working in the   laboratory of Dr. Blaise Boles performing research on Stapphylococcus.
	
	




Publications
	

	
Schmitt D. M, O'Dee D. M, Horzempa J, Carlson P. E, Jr., Russo B. C, Bales J. M, Brown M. J, and Nau G. J. A Francisella tularensis Live Vaccine Strain That Improves Stimulation of Antigen-Presenting Cells Does Not Enhance Vaccine Efficacy. PLoS One. 7: e31172. |  View Abstract
Russo B. C, Horzempa J, O'Dee D. M, Schmitt D. M, Brown M. J, Carlson P. E, Jr., Xavier R. J, and Nau G. J. A Francisella tularensis locus required for spermine responsiveness is necessary for virulence. Infect Immun. 79: 3665-3676. |  View Abstract
Horzempa J, Shanks R. M, Brown M. J, Russo B. C, O'Dee D. M, and Nau G. J. Utilization of an unstable plasmid and the I-SceI endonuclease to generate routine markerless deletion mutants in Francisella tularensis. J Microbiol Methods. 80: 106-108. |  View Abstract