Jeffrey Meteer, PhD

Contact

Mentor

Dr. John Mellors

Dissertation

Activity Profiles & Mechanisms of Resistance of 3’-Azido-2’, 3’-Dideoxynucleoside Analog Reverse Transcriptase Inhibitors of HIV-1

Education

PhD in Molecular Virology and Microbiology, University of Pittsburgh School of Medicine, 2013

BS in Chemistry, Saint John Fisher College, 2006

Research

Abstracts

Meteer, J., Kootnz, D., Schinazi, R.F., Sluis-Cremer, N., Mellors, J.W. "The base component of 3’-azido-2’,3’-dideoxynucleosides determines the mutation patterns selected in HIV-1 reverse transcriptase." Abstract for poster presentation, International HIV and Hepatitis Virus Drug Resistance Workshop & Curative Strategies, Dubrovnik, Croatia. 2010

Meteer, J., Koontz, D., Rapp, K.L., Detorio, M., Ruckstuhl, M., Schinazi, R.F., Mellors, J.W. "Novel resistance profile of the potent nucleoside analogue reverse transcriptase inhibitor 3’-azido-2’,3’-dideoxyguanosine." Abstract for poster presentation, XVII International HIV Drug Resistance Workshop, Sitges, Spain. 2008

Meteer, J. and Meier, P. "Small Molecule Inducers of Organohalide Metabolism by Anaerobic Microorganisms." Abstract for poster presentation, 32nd Northeast Regional Meeting of the American Chemical Society, Rochester, NY, USA. 2004

Publications

Meteer J. D, Koontz D, Asif G, Zhang H. W, Detorio M, Solomon S, Coats S. J, Sluis-Cremer N, Schinazi R. F, and Mellors J. W. The base component of 3'-azido-2',3'-dideoxynucleosides influences resistance mutations selected in HIV-1 reverse transcriptase. Antimicrob Agents Chemother. 55: 3758-3764. | View Abstract

Brehm J. H, Koontz D, Meteer J. D, Pathak V, Sluis-Cremer N, and Mellors J. W. Selection of mutations in the connection and RNase H domains of human immunodeficiency virus type 1 reverse transcriptase that increase resistance to 3'-azido-3'-dideoxythymidine. J Virol. 81: 7852-7859. | View Abstract